Prions §

Group: 4 #group-4

Relations §

• Protein Aggregation: Prions are associated with the abnormal aggregation of misfolded proteins.
• Neurodegenerative Diseases: Prion diseases are a type of neurodegenerative disease caused by prions.
• Misfolded Proteins: Prions are misfolded proteins that can induce other proteins to misfold.
• Spongiform Degeneration: Prion diseases are characterized by spongiform degeneration of the brain, which gives it a sponge-like appearance.
• Creutzfeldt-Jakob Disease: Creutzfeldt-Jakob disease is a fatal neurodegenerative disorder caused by prions.
• Protein Misfolding: Prions are infectious misfolded protein aggregates that can propagate their abnormal conformation to other proteins, causing neurodegenerative diseases.
• Amyloid Fibrils: Prions can form amyloid fibrils, which are insoluble protein aggregates.
• Protein Folding: Prions are misfolded proteins that can propagate their abnormal conformation.
• Prion Strains: Different prion strains can cause distinct disease phenotypes and have varying degrees of transmissibility.
• Prion Diseases: Prion diseases are a group of rare, fatal neurodegenerative disorders caused by prions.
• Proteinaceous Infectious Particles: Prions are proteinaceous infectious particles, meaning they are composed primarily of misfolded proteins.
• Conformational Changes: Prion diseases involve conformational changes in proteins, leading to misfolding and aggregation.
• Folding in Biology: Prions are infectious misfolded protein particles that can cause other proteins to misfold.
• Transmissible Spongiform Encephalopathies: Prion diseases are also known as transmissible spongiform encephalopathies.
• Prion Conversion: Prion conversion is the process by which normal proteins are converted into the misfolded prion form.
• Prion Propagation: Prions can propagate by inducing other proteins to misfold and aggregate, leading to the spread of the disease.
• Prion Replication: Prions can replicate by inducing other proteins to misfold and adopt the same abnormal conformation.
• Protein Misfolding Disorders: Prion diseases are a type of protein misfolding disorder, where proteins adopt an abnormal conformation.
• Chronic Wasting Disease: Chronic wasting disease is a prion disease that affects deer, elk, and other cervids.
• Infectious Agents: Prions are considered infectious agents, as they can transmit their misfolded structure to other proteins.
• Transmissible Diseases: Prion diseases are transmissible, meaning they can be transmitted between individuals or species.
• Mad Cow Disease: Mad cow disease, or bovine spongiform encephalopathy, is a prion disease that affects cattle.