Misfolded Proteins §

Group: 5 #group-5

Relations §

• Oxidative Stress: Misfolded proteins can contribute to oxidative stress, which can further exacerbate protein misfolding.
• Aggregation: Misfolded proteins can form insoluble aggregates that disrupt cellular functions.
• Prions: Prions are misfolded proteins that can induce other proteins to misfold.
• Protein Folding Diseases: Protein folding diseases are caused by the misfolding and aggregation of specific proteins.
• Endoplasmic Reticulum Stress: Misfolded proteins can accumulate in the endoplasmic reticulum, leading to ER stress and the unfolded protein response.
• Protein Aggregation: Protein aggregation involves the abnormal accumulation of misfolded proteins.